Pregnancy outcome in systemic lupus erythematosus: Asia’s largest single centre study
Identifieur interne : 001678 ( Main/Exploration ); précédent : 001677; suivant : 001679Pregnancy outcome in systemic lupus erythematosus: Asia’s largest single centre study
Auteurs : Neelam Aggarwal [Inde] ; Ainharan Raveendran [Inde] ; Vanita Suri [Inde] ; Seema Chopra [Inde] ; Pooja Sikka [Inde] ; Aman Sharma [Inde]Source :
- Archives of Gynecology and Obstetrics [ 0932-0067 ] ; 2011-08-01.
English descriptors
Abstract
Abstract: Aim: To evaluate pregnancy outcome in women with systemic lupus erythematosus (SLE). Methods: A total of 71 pregnancies in 35 women with SLE were evaluated for maternal and perinatal outcomes in a tertiary centre of Northern India. Thirty-five pregnancies were evaluated prospectively while details of previous 36 pregnancies in the same women were studied retrospectively. Results: The Mean age of pregnant women with SLE was 26.89 ± 2.7 years and 14.57% were nulliparous. The presenting event was arthritis in 60% of the patients; others presented with febrile illness, renal manifestation and cutaneous manifestation. One woman was lupus anticoagulant positive. All women conceived while on disease quiescence period and were continued on the same pre-pregnancy dose of pharmacological agents. Hypertensive disorders of pregnancy were seen in 28.5% while chronic hypertension was seen in 5.6%. The incidence of abortion, preterm deliveries and perinatal loss was 33.8, 29.57 and 12.67%, respectively. Vaginal delivery rate was 47.88 and 18.3% underwent caesarean section. There was no case of neonatal lupus and none had disease flare-up in the postpartum period. Conclusion: A better pregnancy outcome can be expected if clinical remission is achieved and disease activity is adequately controlled prior to pregnancy.
Url:
DOI: 10.1007/s00404-010-1618-7
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000585
- to stream Istex, to step Curation: 000585
- to stream Istex, to step Checkpoint: 000623
- to stream Main, to step Merge: 001681
- to stream Main, to step Curation: 001678
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Pregnancy outcome in systemic lupus erythematosus: Asia’s largest single centre study</title><author><name sortKey="Aggarwal, Neelam" sort="Aggarwal, Neelam" uniqKey="Aggarwal N" first="Neelam" last="Aggarwal">Neelam Aggarwal</name></author><author><name sortKey="Raveendran, Ainharan" sort="Raveendran, Ainharan" uniqKey="Raveendran A" first="Ainharan" last="Raveendran">Ainharan Raveendran</name></author><author><name sortKey="Suri, Vanita" sort="Suri, Vanita" uniqKey="Suri V" first="Vanita" last="Suri">Vanita Suri</name></author><author><name sortKey="Chopra, Seema" sort="Chopra, Seema" uniqKey="Chopra S" first="Seema" last="Chopra">Seema Chopra</name></author><author><name sortKey="Sikka, Pooja" sort="Sikka, Pooja" uniqKey="Sikka P" first="Pooja" last="Sikka">Pooja Sikka</name></author><author><name sortKey="Sharma, Aman" sort="Sharma, Aman" uniqKey="Sharma A" first="Aman" last="Sharma">Aman Sharma</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:4841CD4FB2909CE646A0368C9577A62E39A30F77</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1007/s00404-010-1618-7</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-J65G15NN-N/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000585</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000585</idno><idno type="wicri:Area/Istex/Curation">000585</idno><idno type="wicri:Area/Istex/Checkpoint">000623</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000623</idno><idno type="wicri:doubleKey">0932-0067:2010:Aggarwal N:pregnancy:outcome:in</idno><idno type="wicri:Area/Main/Merge">001681</idno><idno type="wicri:Area/Main/Curation">001678</idno><idno type="wicri:Area/Main/Exploration">001678</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Pregnancy outcome in systemic lupus erythematosus: Asia’s largest single centre study</title><author><name sortKey="Aggarwal, Neelam" sort="Aggarwal, Neelam" uniqKey="Aggarwal N" first="Neelam" last="Aggarwal">Neelam Aggarwal</name><affiliation wicri:level="1"><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh</wicri:regionArea><wicri:noRegion>Chandigarh</wicri:noRegion></affiliation><affiliation></affiliation></author><author><name sortKey="Raveendran, Ainharan" sort="Raveendran, Ainharan" uniqKey="Raveendran A" first="Ainharan" last="Raveendran">Ainharan Raveendran</name><affiliation wicri:level="1"><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh</wicri:regionArea><wicri:noRegion>Chandigarh</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Inde</country></affiliation></author><author><name sortKey="Suri, Vanita" sort="Suri, Vanita" uniqKey="Suri V" first="Vanita" last="Suri">Vanita Suri</name><affiliation wicri:level="1"><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh</wicri:regionArea><wicri:noRegion>Chandigarh</wicri:noRegion></affiliation><affiliation></affiliation></author><author><name sortKey="Chopra, Seema" sort="Chopra, Seema" uniqKey="Chopra S" first="Seema" last="Chopra">Seema Chopra</name><affiliation wicri:level="1"><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh</wicri:regionArea><wicri:noRegion>Chandigarh</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Inde</country></affiliation></author><author><name sortKey="Sikka, Pooja" sort="Sikka, Pooja" uniqKey="Sikka P" first="Pooja" last="Sikka">Pooja Sikka</name><affiliation wicri:level="1"><country xml:lang="fr">Inde</country><wicri:regionArea>Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh</wicri:regionArea><wicri:noRegion>Chandigarh</wicri:noRegion></affiliation></author><author><name sortKey="Sharma, Aman" sort="Sharma, Aman" uniqKey="Sharma A" first="Aman" last="Sharma">Aman Sharma</name><affiliation wicri:level="1"><country xml:lang="fr">Inde</country><wicri:regionArea>Rheumatology Wing, Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, 160 012, Chandigarh</wicri:regionArea><wicri:noRegion>Chandigarh</wicri:noRegion></affiliation><affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Archives of Gynecology and Obstetrics</title><title level="j" type="abbrev">Arch Gynecol Obstet</title><idno type="ISSN">0932-0067</idno><idno type="eISSN">1432-0711</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="2011-08-01">2011-08-01</date><biblScope unit="volume">284</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="281">281</biblScope><biblScope unit="page" to="285">285</biblScope></imprint><idno type="ISSN">0932-0067</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0932-0067</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Arthritis</term><term>Azathioprine</term><term>Lupus pregnancy</term><term>Neonatal lupus</term><term>Systemic lupus erythematosus</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Aim: To evaluate pregnancy outcome in women with systemic lupus erythematosus (SLE). Methods: A total of 71 pregnancies in 35 women with SLE were evaluated for maternal and perinatal outcomes in a tertiary centre of Northern India. Thirty-five pregnancies were evaluated prospectively while details of previous 36 pregnancies in the same women were studied retrospectively. Results: The Mean age of pregnant women with SLE was 26.89 ± 2.7 years and 14.57% were nulliparous. The presenting event was arthritis in 60% of the patients; others presented with febrile illness, renal manifestation and cutaneous manifestation. One woman was lupus anticoagulant positive. All women conceived while on disease quiescence period and were continued on the same pre-pregnancy dose of pharmacological agents. Hypertensive disorders of pregnancy were seen in 28.5% while chronic hypertension was seen in 5.6%. The incidence of abortion, preterm deliveries and perinatal loss was 33.8, 29.57 and 12.67%, respectively. Vaginal delivery rate was 47.88 and 18.3% underwent caesarean section. There was no case of neonatal lupus and none had disease flare-up in the postpartum period. Conclusion: A better pregnancy outcome can be expected if clinical remission is achieved and disease activity is adequately controlled prior to pregnancy.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><country name="Inde"><noRegion><name sortKey="Aggarwal, Neelam" sort="Aggarwal, Neelam" uniqKey="Aggarwal N" first="Neelam" last="Aggarwal">Neelam Aggarwal</name></noRegion><name sortKey="Chopra, Seema" sort="Chopra, Seema" uniqKey="Chopra S" first="Seema" last="Chopra">Seema Chopra</name><name sortKey="Chopra, Seema" sort="Chopra, Seema" uniqKey="Chopra S" first="Seema" last="Chopra">Seema Chopra</name><name sortKey="Raveendran, Ainharan" sort="Raveendran, Ainharan" uniqKey="Raveendran A" first="Ainharan" last="Raveendran">Ainharan Raveendran</name><name sortKey="Raveendran, Ainharan" sort="Raveendran, Ainharan" uniqKey="Raveendran A" first="Ainharan" last="Raveendran">Ainharan Raveendran</name><name sortKey="Sharma, Aman" sort="Sharma, Aman" uniqKey="Sharma A" first="Aman" last="Sharma">Aman Sharma</name><name sortKey="Sikka, Pooja" sort="Sikka, Pooja" uniqKey="Sikka P" first="Pooja" last="Sikka">Pooja Sikka</name><name sortKey="Suri, Vanita" sort="Suri, Vanita" uniqKey="Suri V" first="Vanita" last="Suri">Vanita Suri</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001678 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001678 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= ChloroquineV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:4841CD4FB2909CE646A0368C9577A62E39A30F77
|texte= Pregnancy outcome in systemic lupus erythematosus: Asia’s largest single centre study
}}
| This area was generated with Dilib version V0.6.33. |  |